Are Adult Stem Cells Effective?
- Diabetes type 2 was effectively treated after two IV treatments with umbilical cord MSCs. Three year follow up, gold standard, double blind placebo controlled study “Long term effect and safety of Wharton’s jelly-derived mesenchymal stem cells on type 2 diabetes.” (View Abstract) (View Complete Paper – pdf)
- Juvenile rheumatoid arthritis was successfully treated using umbilical cord MSCs. Disease symptoms were reduced and markers of the disease decreased significantly. 2016 study of 10 patients. (View Abstract) (View Complete Paper – pdf)
- Rheumatoid Arthritis (RA) – 172 patient trial, treated with combination of standard medications and umbilical cord MSCs. No adverse events during or after treatment. Study conclusion: “Treatment with DMARDs plus UC-MSCs may provide safe, significant, and persistent clinical benefits for patients with active RA.” (View Abstract)
- 2014 review paper of MSCs to treat acute organ injury. Promising preclinical evidence has resulted in several phase I, phase II and phase III clinical trials that are currently still in progress and will further determine the optimal clinical use of MSCs in the treatment of organ injury. (View Complete Paper – pdf)
- Continuous improvement after multiple mesenchymal stem cell transplantations in a patient with complete spinal cord injury. (View Abstract)
- Results of a Phase I/IIa Clinical Trial for the treatment of amyotrophic lateral sclerosis (ALS, or “Lou Gehrig’s disease”) with autologous bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) yielded further evidence for the safety and efficacy of BM-MSCs in slowing the progression of ALS by providing anti-inflammatory neurotrophic support to spinal motoneurons. (View Abstract) (View Complete Paper – pdf)